SCHEMBL29505896

SCHEMBL29505896

NNc1ccc(C(=O)O)cn1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 17/20 0.67
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57
GABRG1 Q8N1C3 1/20 0.57
GABRG3 Q99928 1/20 0.57
GABRQ Q9UN88 1/20 0.57
HCAR2 Q8TDS4 2/20 0.56
P4HA1 P13674 2/20 0.55
P4HTM Q9NXG6 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158601 1.00 HCAR3 (0.67) HCAR3GABRPGABRDGABRA1GABRB1
Ammonia Solution, Strong SCHEMBL28249483 0.98 HCAR3 (0.65) HCAR3GABRPGABRDGABRA1GABRB1
Hydrochloric Acid SCHEMBL5789616 0.98 HCAR3 (0.65) HCAR3GABRPGABRDGABRA1GABRB1
Acetone SCHEMBL7024428 0.94 HCAR3 (0.66) HCAR3GABRPGABRDGABRA1GABRB1
Succinic Acid SCHEMBL23070477 0.91 HCAR3 (0.57) HCAR3GABRPGABRDGABRA1GABRB1
Succinimide SCHEMBL28163974 0.87 HCAR3 (0.53) HCAR3GABRPGABRDGABRA1GABRB1
Succinimide SCHEMBL25397856 0.86 HCAR3 (0.51) HCAR3GABRPGABRDGABRA1GABRB1
Benzaldehyde SCHEMBL27567924 0.86 HCAR3 (0.55) HCAR3GABRPGABRDGABRA1GABRB1
SCHEMBL8722229 0.84 NNMT (0.50) HCAR3HCAR2
SCHEMBL383413 0.84 NNMT (0.70) HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 US claimed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 US claimed
EP-4412996-A1 RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS Philochem AG (CH) 2024-08-14 EP claimed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 US claimed
US-11896683-B2 Radiolabelled material for targeted administration THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2024-02-13 US claimed
WO-2023057457-A1 RADIOLABELLED FIBROBLAST ACTIVATION PROTEIN LIGANDS PHILOCHEM AG (CH) 2023-04-13 WO claimed
CN-110290816-B Radiolabelled materials for targeted administration 澳大利亚国立大学 2022-09-30 CN claimed
US-12636386-B2 Compositions and methods for the treatment and imaging of cancer BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-05-26 US disclosed
EP-3634474-B1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL EUROPE GMBH (DE) 2026-05-06 EP disclosed
US-12569576-B2 Compositions and methods for measuring oxidative stress WASHINGTON UNIVERSITY (US) 2026-03-10 US disclosed
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 US disclosed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP disclosed
EP-4587062-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA Cellis AG (CH) 2025-07-23 EP disclosed
WO-2022152701-A1 COMBINATION THERAPY F. HOFFMANN-LA ROCHE AG (CH) 2022-07-21 WO disclosed
WO-2022152656-A1 SPLIT ANTIBODIES WHICH BIND TO CANCER CELLS AND TARGET RADIONUCLIDES TO SAID CELLS F. HOFFMANN-LA ROCHE AG (CH) 2022-07-21 WO disclosed
WO-2022150443-A1 FOLATE RECEPTOR-TARGETED CONJUGATES, COMPOSITIONS, AND DELIVERY TO THE CENTRAL NERVOUS SYSTEM PURDUE RESEARCH FOUNDATION (US) 2022-07-14 WO disclosed
EP-3997130-A1 ANTIBODIES WHICH BIND TO CANCER CELLS AND TARGET RADIONUCLIDES TO SAID CELLS F. Hoffmann-La Roche AG (CH) 2022-05-18 EP disclosed
EP-3993839-A1 RADIOPHARMACEUTICAL COMPOUND AND COMPOSITION FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING OF INTERLEUKIN-2 RECEPTOR POSITIVE CELLS, PROCESS FOR THE PREPARATION THEREOF, RELATED KIT AND USES THEREOF Sapienza Universita di Roma (IT) 2022-05-11 EP disclosed
CN-114341188-A Antibodies that bind to cancer cells and target radionuclides to said cells 豪夫迈·罗氏有限公司 2022-04-12 CN disclosed
WO-2022058308-A1 METHOD AND KIT FOR DETECTING TOXINS AND PATHOGENS BY LIGAND BINDING ASSAYS USING DEFORMABLE COLLODIAL PARTICLES Technische Universität Dresden (DE) 2022-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569576-B2 Compositions and methods for measuring oxidative stress MPO, LPO, GPX1 HCAR3 3787/4885GABRP 3800/4885GABRD 4705/4885
US-12016935-B2 Methods for detecting CCR2 receptors CCR2, CCR1, CCR5 HCAR3 129/4885GABRP 1065/4885GABRD 1588/4885
US-11896683-B2 Radiolabelled material for targeted administration MPI, PBRM1, PCNA HCAR3 1686/4885GABRP 2834/4885GABRD 4474/4885
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR5 HCAR3 129/4885GABRP 1065/4885GABRD 1588/4885
US-12636386-B2 Compositions and methods for the treatment and imaging of cancer GBA1, GALC, CD47 HCAR3 2501/4885GABRP 2669/4885GABRD 3729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.