Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939743 | 0.81 | MAPT (0.49) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL8339251 | 0.80 | MAPT (0.51) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL1190605 | 0.74 | MAPT (0.52) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL27923841 | 0.72 | TDP1 (0.50) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL510440 | 0.72 | MAPT (0.50) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL7285309 | 0.72 | MAPT (0.50) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL28006544 | 0.72 | LTA4H (0.53) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL3211927 | 0.72 | MAPT (0.50) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL7293597 | 0.72 | MAPT (0.59) | LIPEMAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL11752081 | 0.72 | RXRA (0.48) | LIPEMAPTTDP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108656-B | N- substitution -3,5- disubstituted benzenes Carbox amide and its preparation method and application | 中国科学院上海药物研究所 | 2019-11-05 | — | — | CN | disclosed |
| CN-107108656-A | N replaces 3,5 disubstituted benzenes Carbox amides and its preparation method and application | 中国科学院上海药物研究所 | 2017-08-29 | — | — | CN | disclosed |