Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.88 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045417 | 0.86 | MAPT (0.70) | ALDH1A1MAPTGAAL3MBTL1MAOB | |
| SCHEMBL18868405 | 0.86 | L3MBTL1 (1.00) | ALDH1A1MAPTGAAL3MBTL1MAOB | |
| SCHEMBL7392055 | 0.85 | ALDH1A1 (0.68) | ALDH1A1MAPTGAAL3MBTL1MAOB | |
| SCHEMBL2744788 | 0.84 | RAB9A (0.72) | ALDH1A1MAPTGAAL3MBTL1HDAC1 | |
| SCHEMBL20463317 | 0.83 | ALDH1A1 (0.74) | ALDH1A1MAPTL3MBTL1MAOBRAB9A | |
| SCHEMBL163209 | 0.82 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL7387284 | 0.82 | HRH3 (0.66) | ALDH1A1MAPTL3MBTL1MAOBHRH2 | |
| SCHEMBL7983991 | 0.82 | HRH3 (0.66) | ALDH1A1MAPTL3MBTL1MAOBHRH2 | |
| SCHEMBL5526919 | 0.82 | HRH3 (0.66) | ALDH1A1MAPTL3MBTL1MAOBHRH2 | |
| SCHEMBL12408526 | 0.82 | HRH3 (0.66) | ALDH1A1MAPTL3MBTL1MAOBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249402-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEPOROSIS COMPRISING THE SAME | DONG WHA PHARMACEUTICAL CO. LTD. (KR) | 2010-09-30 | — | — | US | disclosed |
| EP-2170878-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | Dong Wha Pharmaceutical Co., Ltd. (KR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009017346-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249402-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEPOROSIS COMPRISING THE SAME | SOST, CTSA, BECN1 | ALDH1A1 3402/4885MAPT 3701/4885GAA 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.