Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091030 | 0.85 | ADORA2A (0.40) | IDO1ADORA2ATDO2SMN1; SMN2MAPT | |
| SCHEMBL28216799 | 0.82 | MAPT (0.42) | IDO1ADORA2ATDO2SMN1; SMN2MAPT | |
| SCHEMBL14907942 | 0.82 | DPP4 (0.46) | IDO1TDO2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL28003562 | 0.82 | CASP6 (0.41) | IDO1ADORA2ATDO2SMN1; SMN2MAPT | |
| SCHEMBL17198791 | 0.81 | SMN1; SMN2 (0.44) | IDO1ADORA2ATDO2SMN1; SMN2MAPT | |
| SCHEMBL4518530 | 0.76 | SCN9A (0.45) | ADORA2ASMN1; SMN2MAPTNPC1KDM4E | |
| SCHEMBL466425 | 0.76 | IDO1 (0.46) | IDO1TDO2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4533675 | 0.76 | METAP2 (0.46) | IDO1TDO2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL29430087 | 0.76 | METAP2 (0.46) | IDO1TDO2SMN1; SMN2MAPTNPC1 | |
| SCHEMBL4518539 | 0.73 | LMNA (0.53) | IDO1TDO2SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501204-A | A kind of method that 1,3 substituted thiazole cyclics are synthesized by styrene compound | 河南师范大学 | 2017-12-22 | — | — | CN | disclosed |
| CN-107105657-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |