Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.46 |
| ▸ | METAP1 | P53582 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430087 | 1.00 | METAP2 (0.46) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL27545633 | 0.83 | METAP1 (0.40) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL28363719 | 0.82 | CD44 (0.39) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL17194903 | 0.79 | METAP1 (0.40) | METAP2METAP1IDO1ALDH1A1HSD17B10 | |
| SCHEMBL28857133 | 0.78 | METAP1 (0.44) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL4518539 | 0.78 | LMNA (0.53) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL14754323 | 0.77 | METAP1 (0.49) | METAP2METAP1ALDH1A1TSHRNPC1 | |
| SCHEMBL14754485 | 0.77 | METAP1 (0.49) | METAP2METAP1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL21091024 | 0.77 | CASP6 (0.45) | METAP2METAP1IDO1CYP1A2CYP2D6 | |
| SCHEMBL31006742 | 0.77 | METAP1 (0.49) | METAP2METAP1ALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-3495358-B1 | AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-107501204-A | A kind of method that 1,3 substituted thiazole cyclics are synthesized by styrene compound | 河南师范大学 | 2017-12-22 | — | — | CN | disclosed |
| EP-2170309-B1 | 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL | HYDRA BIOSCIENCES INC (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. | 2013-03-07 | — | — | US | disclosed |
| CN-101410375-B | Process for producing aromatic compound | SUMITOMO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101287566-B | Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film | TOYO INK MFG CO | 2012-05-23 | — | — | CN | disclosed |
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. | 2012-05-03 | — | — | US | disclosed |
| CN-100516064-C | Kinase inhibitors | LILLY CO ELI (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101410375-A | Process for producing aromatic compound | SUMITOMO CHEMICAL CO (JP) | 2009-04-15 | — | — | CN | disclosed |
| CN-101287566-A | Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film | TOYO INK MFG CO (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1938302-A | Kinase inhibitors | LILLY CO ELI (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1006386-B | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | SHINETSU CHEM IND CO (JP) | 1990-01-10 | — | — | CN | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | METAP2 2696/4885METAP1 3165/4885IDO1 3851/4885 |
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | METAP2 2696/4885METAP1 3165/4885IDO1 3851/4885 |
| US-20130165427-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | METAP2 2696/4885METAP1 3165/4885IDO1 3851/4885 |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | METAP2 1460/4885METAP1 2279/4885IDO1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.