SCHEMBL28166341

SCHEMBL28166341

N#CC(C=O)c1ccc(CCC(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.47
KEAP1 Q14145 1/20 0.46
FFAR4 Q5NUL3 4/20 0.45
NPSR1 Q6W5P4 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28165995 0.84 CA2 (0.48) FFAR1CA2
SCHEMBL31477474 0.76 FFAR1 (0.52) FFAR1KEAP1FFAR4NPSR1CA1
SCHEMBL8993063 0.76 CALM1 (0.41) CA1CA2
SCHEMBL15330263 0.75 CYP2A6 (0.44) CA2
SCHEMBL11449880 0.75 ESR1 (0.37)
SCHEMBL69746 0.73 FFAR1 (0.81) FFAR1KEAP1FFAR4CA1CA2
SCHEMBL8103555 0.73 P2RY2 (0.38) FFAR1
Hydroxyphenyl Propionic Acid SCHEMBL18263865 0.72 FFAR1 (0.65) FFAR1KEAP1FFAR4CA1CA2
SCHEMBL9489967 0.72 TSHR (0.46) NPSR1
SCHEMBL544445 0.72 TSHR (0.46) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107024834-A Compound and coloured composition 住友化学株式会社 2017-08-08 CN disclosed