Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692457 | 0.73 | AKR1C3 (0.40) | TDP1ALDH1A1PPARGMAPK10KMT2A | |
| SCHEMBL15933318 | 0.71 | ALDH1A1 (0.43) | TDP1LMNAALDH1A1PPARGMAPK10 | |
| SCHEMBL15930178 | 0.68 | ALDH1A1 (0.37) | TDP1LMNAALDH1A1PPARGMAPK10 | |
| SCHEMBL3988944 | 0.67 | LMNA (0.39) | TDP1LMNAGLAALDH1A1POLB | |
| SCHEMBL21379809 | 0.67 | TDP1 (0.34) | TDP1LMNAGLAALDH1A1POLB | |
| SCHEMBL909646 | 0.65 | KCNJ1 (0.46) | TDP1LMNAGLAALDH1A1POLB | |
| Bromide SCHEMBL18010906 | 0.64 | KCNJ1 (0.45) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL30061281 | 0.63 | ALDH1A1 (0.40) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL16547534 | 0.63 | TDO2 (0.39) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL1782525 | 0.63 | ALDH1A1 (0.45) | TDP1LMNAGLAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857681-B | It is used as the new big ring of factor XI, plasma thromboplastin antecedent A inhibitor | 百时美施贵宝公司 | 2017-07-14 | — | — | CN | disclosed |