Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909646 | 0.73 | KCNJ1 (0.46) | LMNAGLANOTUMTDP1HSD17B10 | |
| Bromide SCHEMBL18010906 | 0.72 | KCNJ1 (0.45) | LMNAGLANOTUMTDP1HSD17B10 | |
| SCHEMBL1782525 | 0.71 | ALDH1A1 (0.45) | LMNAGLANOTUMTDP1HSD17B10 | |
| SCHEMBL4205737 | 0.68 | LMNA (0.37) | LMNAGLATDP1HSD17B10ALDH1A1 | |
| SCHEMBL1245039 | 0.67 | LMNA (0.46) | LMNAGLATDP1HSD17B10ALDH1A1 | |
| SCHEMBL28166349 | 0.67 | TDP1 (0.34) | LMNAGLATDP1HSD17B10ALDH1A1 | |
| SCHEMBL1698688 | 0.67 | NOTUM (0.35) | NOTUMHSD17B10ALDH1A1KEAP1 | |
| SCHEMBL6072194 | 0.65 | NOTUM (0.41) | LMNANOTUMHSD17B10ALDH1A1TSHR | |
| SCHEMBL28204860 | 0.65 | CYP2A6 (0.39) | LMNAGLATDP1HSD17B10ALDH1A1 | |
| SCHEMBL24937193 | 0.65 | GRM5 (0.51) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108347943-A | HEPATITIS B CORE PROTEIN MODULATORS | 组装生物科学股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2009067493-A2 | 1,3,5 TRI-SUBTITUTED BENZENES FOR TREATMENT OF ALZHEIMER'S DISEASE AND OTHER DISORDERS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |