SCHEMBL28166381

SCHEMBL28166381

FC1=C(F)C(F)c2cccc(F)c21

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
KDM1A O60341 2/20 0.32
KDM1B Q8NB78 1/20 0.32
PDK2 Q15119 1/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7516104 0.70 CHRNB2 (0.42) CHRNB2CHRNA4HTR2CHTR2BKDM1A
SCHEMBL6277880 0.69
SCHEMBL5613617 0.68 GPR3 (0.33) HTR2BKDM1AKDM1B
SCHEMBL28619081 0.67 CA1 (0.40) HTR2CHTR2BPDK2TTR
SCHEMBL9811069 0.64 PPIA (0.43) CHRNB2CHRNA4KDM1AKDM1BPDK2
Ammonia Solution, Strong SCHEMBL19066104 0.61 HTR2C (0.31) HTR2CHTR2BKDM1AKDM1B
SCHEMBL208466 0.60 CA1 (0.44) HTR2CHTR2BPDK2TTR
SCHEMBL13224382 0.60 CHRNB2 (0.42) CHRNB2CHRNA4HTR2CHTR2BKDM1A
SCHEMBL22129686 0.59 CA1 (0.48) PDK2TTR
SCHEMBL30829186 0.58 MEN1 (0.35) HTR2BKDM1AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925663-A Organic compound, liquid crystal composition and liquid crystal display panel TCL华星光电技术有限公司 2023-04-07 CN disclosed
CN-115925663-A Organic compound, liquid crystal composition and liquid crystal display panel TCL华星光电技术有限公司 2023-04-07 CN disclosed
CN-109694420-A Catalyst system and pre-polymerized catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2019-04-30 CN disclosed
CN-107129549-A Ingredient of solid catalyst, catalyst and application for olefinic polymerization 中国石油化工股份有限公司 2017-09-05 CN disclosed
CN-107129547-A Ingredient of solid catalyst, catalyst and application for olefinic polymerization 中国石油化工股份有限公司 2017-09-05 CN disclosed