Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359049 | 0.76 | GPR3 (0.46) | GPR3HTR2AHTR7HTR2BBCHE | |
| SCHEMBL29797969 | 0.76 | GPR3 (0.46) | GPR3HTR2AHTR7HTR2BBCHE | |
| SCHEMBL5067175 | 0.73 | — | — | |
| SCHEMBL28884898 | 0.70 | PIM1 (0.45) | — | |
| SCHEMBL10863356 | 0.68 | MAOA (0.44) | GPR3HTR2AHTR7HTR2BHDAC3 | |
| SCHEMBL19926520 | 0.68 | MEN1 (0.42) | HTR7HTR2BTNKS2BCHE | |
| SCHEMBL10863105 | 0.68 | S100A4 (0.37) | GPR3HTR2ATNKS2KDM1AKDM1B | |
| SCHEMBL19934228 | 0.68 | GPR3 (0.34) | GPR3HTR2AHTR7HTR2BHDAC3 | |
| SCHEMBL4011644 | 0.67 | HTR7 (0.30) | GPR3HTR2AHTR7HTR2B | |
| SCHEMBL9811069 | 0.67 | PPIA (0.43) | GPR3HTR2ATNKS2KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7182885-B2 | Fluorinated indenes and 1,7-dihydroindacenes of negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | disclosed |
| US-20030222243-A1 | Fluorinated indenes and 1,7-dihydroindacenes of negative dielectric anisotrophy | MERCK PATENT GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030222243-A1 | Fluorinated indenes and 1,7-dihydroindacenes of negative dielectric anisotrophy | ZYX, CCNY, LBR | GPR3 2398/4885HTR2A 939/4885HTR7 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.