Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL14763944 | 0.67 | CALM1 (1.00) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Diphenylmethane SCHEMBL1303 | 0.67 | CALM1 (1.00) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Diphenylmethane SCHEMBL4361124 | 0.67 | CALM1 (1.00) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Diphenylmethane SCHEMBL3792579 | 0.67 | CALM1 (1.00) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL62125 | 0.67 | ALDH1A1 (0.69) | CALM1ALDH1A1LOXL2MAOBHPGD | |
| Benzene SCHEMBL3440179 | 0.67 | ALDH1A1 (0.69) | CALM1ALDH1A1LOXL2MAOBHPGD | |
| SCHEMBL9741303 | 0.67 | ALDH1A1 (0.69) | CALM1ALDH1A1LOXL2MAOBHPGD | |
| SCHEMBL5951003 | 0.67 | CALM1 (0.50) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL1728429 | 0.67 | CALM1 (0.50) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL11240991 | 0.67 | CALM1 (0.50) | CALM1TSHRALDH1A1LOXL2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139660-A | Composition for preparing an antitumor agent and method for preparing an antitumor agent based on said composition | 杰尔曼·彼得罗维奇·贝克尔 | 2019-08-16 | — | — | CN | claimed |
| CN-110139660-A | Composition for preparing an antitumor agent and method for preparing an antitumor agent based on said composition | 杰尔曼·彼得罗维奇·贝克尔 | 2019-08-16 | — | — | CN | disclosed |
| CN-109789135-A | ISOQUINOLINE DERIVATIVES AS PERK INHIBITORS | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109608443-A | Heterocycleamide as protein modulator | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-106459131-B | Cyclic annular dinucleotides as STING regulator | 葛兰素史克知识产权开发有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109563151-A | Methods and compositions for treating cancer | 瓦尔希伯伦私人肿瘤研究基金会 | 2019-04-02 | — | — | CN | disclosed |
| CN-109071514-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107849084-A | Ring-type purine dinucleotides as STING conditioning agents | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107108684-A | Particularly for the ring-type dinucleotides for the treatment of cancer | 葛兰素史克知识产权开发有限公司 | 2017-08-29 | — | — | CN | disclosed |