SCHEMBL5951003

SCHEMBL5951003

c1ccc(C[Ge]Cc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.45
LOXL2 Q9Y4K0 2/20 0.45
IDO1 P14902 2/20 0.45
TP53 P04637 1/20 0.45
TRPA1 O75762 1/20 0.45
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2466185 0.97 CALM1 (0.47) CALM1TSHRALDH1A1LOXL2IDO1
Benzene SCHEMBL3440179 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
Diphenylmethane SCHEMBL4361124 0.67 CALM1 (1.00) CALM1TSHRALDH1A1LOXL2IDO1
Diphenylmethane SCHEMBL1303 0.67 CALM1 (1.00) CALM1TSHRALDH1A1LOXL2IDO1
Diphenylmethane SCHEMBL14763944 0.67 CALM1 (1.00) CALM1TSHRALDH1A1LOXL2IDO1
Diphenylmethane SCHEMBL3792579 0.67 CALM1 (1.00) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL62125 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
SCHEMBL9741303 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
Bromide SCHEMBL9007158 0.67 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL29788151 0.67 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7019157-B2 Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process CHISSO CORPORATION (JP) 2006-03-28 US disclosed
US-6995279-B2 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes CHISSO CORPORATION (JP) 2006-02-07 US disclosed
US-20040127731-A1 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes CHISSO CORPORATION (JP) 2004-07-01 US disclosed
US-20030149200-A1 Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process CHISSO PETROCHEMICAL CORPORATION 2003-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149200-A1 Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process ZYX, MLX, ZFX CALM1 4212/4885TSHR 4243/4885ALDH1A1 862/4885
US-20040127731-A1 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes MLX, ZYX, YBX1 CALM1 4154/4885TSHR 4812/4885ALDH1A1 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.