Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554460 | 0.86 | KDM4E (0.64) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL9356013 | 0.86 | MAPT (0.67) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL9283208 | 0.77 | MAPT (0.69) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL11544710 | 0.75 | MAPT (0.67) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL3138995 | 0.73 | KDM4E (0.64) | MAPTKDM4EGLATDP1ALDH1A1 | |
| SCHEMBL11251929 | 0.73 | MAPT (0.70) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL20952296 | 0.73 | MAOB (0.84) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL388018 | 0.72 | ENPP2 (0.86) | LMNAMELKENPP2PTGS2PTGS1 | |
| SCHEMBL30887104 | 0.71 | MAPT (0.53) | MAOBMAPTKDM4EGLATDP1 | |
| SCHEMBL3139976 | 0.71 | ALDH1A1 (0.71) | MAOBMAPTKDM4EGLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918935-B | dihydropyrazole GPR40 modulators | 百时美施贵宝公司 | 2017-07-28 | — | — | CN | disclosed |