Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167401 | 1.00 | LMNA (0.37) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL28361461 | 1.00 | LMNA (0.37) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL28364875 | 1.00 | LMNA (0.37) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL28171272 | 1.00 | LMNA (0.37) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL28338187 | 0.96 | TRPM8 (0.39) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL17537154 | 0.87 | LMNA (0.37) | LMNAKMT2ATRPM8SLC6A2 | |
| SCHEMBL28171399 | 0.83 | FFAR1 (0.33) | LMNAKMT2ATRPM8ALOX5NOTUM | |
| SCHEMBL28171398 | 0.83 | FFAR1 (0.33) | LMNAKMT2ATRPM8ALOX5NOTUM | |
| SCHEMBL28392659 | 0.79 | ALOX15 (0.37) | LMNAKMT2ATRPM8ALOX5UBE2M | |
| SCHEMBL17962437 | 0.79 | KMT2A (0.40) | LMNAKMT2ATRPM8ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074675-B | Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-107074675-A | Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol | 四川海思科制药有限公司 | 2017-08-18 | — | — | CN | disclosed |