Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18263186 | 0.91 | ALOX5 (0.46) | KMT2ALMNAALOX5ALDH1A1TRPM8 | |
| SCHEMBL18263185 | 0.91 | ALOX5 (0.46) | KMT2ALMNAALOX5ALDH1A1TRPM8 | |
| SCHEMBL28364875 | 0.79 | LMNA (0.37) | KMT2ALMNAALOX5TRPM8 | |
| SCHEMBL28167401 | 0.79 | LMNA (0.37) | KMT2ALMNAALOX5TRPM8 | |
| SCHEMBL28171272 | 0.79 | LMNA (0.37) | KMT2ALMNAALOX5TRPM8 | |
| SCHEMBL28361461 | 0.79 | LMNA (0.37) | KMT2ALMNAALOX5TRPM8 | |
| SCHEMBL28167397 | 0.79 | LMNA (0.37) | KMT2ALMNAALOX5TRPM8 | |
| SCHEMBL28392659 | 0.76 | ALOX15 (0.37) | KMT2ALMNAALOX5ALDH1A1TRPM8 | |
| SCHEMBL28338187 | 0.73 | TRPM8 (0.39) | KMT2ALMNAALOX5TRPM8MTOR | |
| SCHEMBL18263192 | 0.69 | TRPM8 (0.38) | KMT2ALMNAALOX5ALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108483-B | Preparation method and intermediate of 2- [ 1-cycloalkylethyl ] phenol | 四川海思科制药有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-107074675-B | Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-107108483-A | A kind of Preparation Method And Their Intermediate of 2 [1 cycloalkylethyl] phenol | 四川海思科制药有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107074675-A | Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol | 四川海思科制药有限公司 | 2017-08-18 | — | — | CN | disclosed |
| WO-2016119757-A1 | METHOD FOR PREPARING 2-[1-CYCLOALKYLETHYL] PHENOL AND INTERMEDIATE THEREOF | 四川海思科制药有限公司 | 2016-08-04 | — | — | WO | disclosed |
| WO-2016119758-A1 | METHOD FOR PREPARING CHIRAL 2-[1-CYCLOPROPYLETHYL]-6-ISOPROPYL-PHENOL | 四川海思科制药有限公司 | 2016-08-04 | — | — | WO | disclosed |