Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812979 | 0.90 | MAPT (0.40) | CA12CA1CA2CA9GPR174 | |
| SCHEMBL17957266 | 0.90 | MAPT (0.43) | FFAR1CA12CA1CA2CA9 | |
| SCHEMBL2813209 | 0.90 | LMNA (0.47) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2815561 | 0.90 | MAPT (0.44) | GPR174MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2816767 | 0.90 | MEN1 (0.43) | CA12CA1CA2CA9GPR174 | |
| SCHEMBL2816790 | 0.88 | SAE1 (0.49) | GRIN1GRIN2BCA12CA1CA2 | |
| SCHEMBL2814844 | 0.87 | EPHX2 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2815366 | 0.87 | IDH1 (0.49) | FFAR1ALDH1A1MAPT | |
| SCHEMBL2816333 | 0.87 | RAB9A (0.43) | CA12CA1CA2CA9GPR174 | |
| SCHEMBL2815483 | 0.86 | MEN1 (0.48) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | SDHA, SDHB, TPD52L2 | GRIN1 1886/4885GRIN2B 2449/4885FFAR1 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.