Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635975 | 0.89 | SIGMAR1 (0.58) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| SCHEMBL15994202 | 0.84 | SIGMAR1 (0.59) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| SCHEMBL16293808 | 0.84 | SIGMAR1 (0.58) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| SCHEMBL16006929 | 0.83 | SIGMAR1 (0.57) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| SCHEMBL16293099 | 0.76 | SIGMAR1 (0.47) | SIGMAR1POLBMEN1KMT2ACCR8 | |
| SCHEMBL20779104 | 0.75 | SIGMAR1 (0.43) | SIGMAR1POLBUSP2ALDH1A1MEN1 | |
| SCHEMBL19574680 | 0.74 | TSHR (0.43) | SIGMAR1POLBUSP2GAA | |
| SCHEMBL15637477 | 0.73 | CCR2 (0.46) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| Isonicotinic Acid SCHEMBL28168926 | 0.72 | SIGMAR1 (0.54) | SIGMAR1CCR2POLBUSP2MCHR1 | |
| SCHEMBL17984984 | 0.70 | SIGMAR1 (0.42) | SIGMAR1CCR2POLBUSP2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434803-A | Histone demethylase inhibitor | 吉利德科学公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-104981458-B | Inhibitors of histone demethylases | 吉利德科学公司 | 2017-07-21 | — | — | CN | disclosed |