Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861727 | 0.76 | CARM1 (0.34) | KDM4EPKMKMT2AALDH1A1CARM1 | |
| SCHEMBL27772931 | 0.73 | EPHX2 (0.37) | ICAM1DDR1 | |
| SCHEMBL8081771 | 0.73 | — | — | |
| SCHEMBL28247557 | 0.72 | GNAI3 (0.38) | KDM4EPKMKMT2AALDH1A1CARM1 | |
| SCHEMBL8219816 | 0.69 | CA12 (0.68) | CA12CA7CA14KDM4ECA1 | |
| SCHEMBL27748503 | 0.69 | LTA4H (0.35) | — | |
| SCHEMBL27969225 | 0.69 | KCNH2 (0.35) | KDM4EPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL27748345 | 0.69 | HRH3 (0.36) | PKMALDH1A1DDR1CARM1PRMT6 | |
| SCHEMBL28858425 | 0.69 | HRH3 (0.36) | PKMALDH1A1DDR1CARM1PRMT6 | |
| SCHEMBL28190250 | 0.69 | HRH3 (0.36) | PKMALDH1A1DDR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-A | Phenylpropionyl amine derivant, its preparation method and its in application pharmaceutically | 江苏恒瑞医药股份有限公司 | 2017-08-29 | — | — | CN | disclosed |