Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748375 | 0.82 | HTR2A (0.33) | HTR2AHTR2CKCNH2 | |
| SCHEMBL27930025 | 0.79 | JAK1 (0.33) | — | |
| SCHEMBL28224324 | 0.78 | L3MBTL1 (0.35) | — | |
| SCHEMBL12935790 | 0.77 | SMN1; SMN2 (0.45) | LTA4HHTR2A | |
| SCHEMBL21766785 | 0.77 | SMN1; SMN2 (0.33) | LTA4HHTR2AHTR2CKCNH2CYP11B2 | |
| SCHEMBL12465710 | 0.76 | SLC18A3 (0.41) | LTA4HHTR2AHTR2CKCNH2 | |
| SCHEMBL28833655 | 0.76 | HRH3 (0.40) | — | |
| SCHEMBL28777002 | 0.75 | CA12 (0.38) | — | |
| SCHEMBL27342995 | 0.75 | LTA4H (0.36) | LTA4HHTR2AHTR2CKCNH2 | |
| SCHEMBL27896503 | 0.74 | EPHX2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479274-A | Pharmaceutical compounds | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |