Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PIEZO1 | Q92508 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948877 | 0.85 | IDO1 (0.48) | P2RX7IDO1GRM5PIEZO1NPY5R | |
| SCHEMBL27411097 | 0.83 | NPY5R (0.42) | P2RX7KDM4EPIEZO1NPY5R | |
| SCHEMBL29712840 | 0.82 | P2RX7 (0.42) | P2RX7IDO1CNR2GRM5KDM4E | |
| SCHEMBL28627684 | 0.82 | P2RX7 (0.42) | P2RX7IDO1CNR2GRM5KDM4E | |
| SCHEMBL24181568 | 0.82 | P2RX7 (0.46) | P2RX7CNR2PIEZO1 | |
| SCHEMBL30066169 | 0.82 | P2RX7 (0.46) | P2RX7CNR2PIEZO1 | |
| SCHEMBL6662455 | 0.82 | ALOX5AP (0.42) | P2RX7PIEZO1NPY5R | |
| SCHEMBL31444423 | 0.82 | ALOX5AP (0.45) | P2RX7PIEZO1PTPN11 | |
| SCHEMBL2335710 | 0.82 | PIEZO1 (0.42) | P2RX7PIEZO1 | |
| SCHEMBL7486893 | 0.78 | PIEZO1 (0.47) | P2RX7KDM4EPIEZO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109706453-B | Application of benzopyrazine compound in copper surface roughening and composition containing benzopyrazine compound for copper surface roughening | 广东东硕科技有限公司 | 2021-02-23 | — | — | CN | claimed |
| CN-109706453-B | Application of benzopyrazine compound in copper surface roughening and composition containing benzopyrazine compound for copper surface roughening | 广东东硕科技有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-109983001-A | 2, 5-disubstituted 3-methylpyrazine and 2,5, 6-trisubstituted 3-methylpyrazine as allosteric SHP2 inhibitors | 锐新医药公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-107011273-A | The method of one kind synthesis amine of 6 iodine 3 (2,3 dichlorophenyl) pyrazine 2 | 无锡捷化医药科技有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-107011273-A | The method of one kind synthesis amine of 6 iodine 3 (2,3 dichlorophenyl) pyrazine 2 | 无锡捷化医药科技有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-107011273-A | The method of one kind synthesis amine of 6 iodine 3 (2,3 dichlorophenyl) pyrazine 2 | 无锡捷化医药科技有限公司 | 2017-08-04 | — | — | CN | disclosed |