SCHEMBL28170365

SCHEMBL28170365

O=C(O)c1ccc(C(=O)O)c(C2CC2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
CAMKK2 Q96RR4 7/20 0.44
CREBBP Q92793 1/20 0.44
RARG P13631 2/20 0.43
RARB P10826 1/20 0.43
KMO O15229 1/20 0.42
MYC P01106 1/20 0.42
CAMKK1 Q8N5S9 5/20 0.41
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
PTGS2 P35354 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29154739 1.00 KDM4E (0.46) KDM4ECAMKK2CREBBPRARGRARB
SCHEMBL2445552 0.93 CAMKK2 (0.49) KDM4ECAMKK2KMOCAMKK1ALDH1A1
SCHEMBL28170978 0.93 CAMKK2 (0.52) KDM4ECAMKK2KMOCAMKK1
SCHEMBL29470084 0.93 CAMKK2 (0.49) KDM4ECAMKK2KMOCAMKK1ALDH1A1
SCHEMBL30952631 0.91 KMO (0.54) CAMKK2KMOCAMKK1
SCHEMBL448284 0.91 KMO (0.54) CAMKK2KMOCAMKK1
SCHEMBL27879994 0.89 CREBBP (0.41) KDM4ECAMKK2CREBBPRARGRARB
Methyl Alcohol SCHEMBL31596316 0.88 KMO (0.51) CAMKK2KMOCAMKK1
SCHEMBL31039577 0.87 CREBBP (0.40) KDM4ECAMKK2CREBBPRARGRARB
SCHEMBL16584859 0.87 CAMKK2 (0.43) CAMKK2RARGRARBCAMKK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105764883-B Thermoplastic polymer composition 美利肯公司 2019-06-04 CN disclosed
CN-105764971-B Thermoplastic polymer composition 美利肯公司 2018-04-06 CN disclosed
CN-105745264-B Thermoplastic polymer composition 美利肯公司 2018-03-13 CN disclosed
CN-105745189-B Thermoplastic polymer composition 美利肯公司 2017-11-21 CN disclosed