SCHEMBL2445552

SCHEMBL2445552

O=C(O)c1ccc(C(=O)O)c(C2CCC2)c1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CAMKK2 Q96RR4 15/20 0.49
KMO O15229 1/20 0.47
CAMKK1 Q8N5S9 12/20 0.45
ACMSD Q8TDX5 2/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470084 1.00 CAMKK2 (0.49) CAMKK2KMOCAMKK1ACMSDKDM4E
SCHEMBL28170978 0.96 CAMKK2 (0.52) CAMKK2KMOCAMKK1ACMSDKDM4E
SCHEMBL448284 0.95 KMO (0.54) CAMKK2KMOCAMKK1ACMSD
SCHEMBL30952631 0.95 KMO (0.54) CAMKK2KMOCAMKK1ACMSD
SCHEMBL29154739 0.93 KDM4E (0.46) CAMKK2KMOCAMKK1KDM4EALDH1A1
SCHEMBL28170365 0.93 KDM4E (0.46) CAMKK2KMOCAMKK1KDM4EALDH1A1
Methyl Alcohol SCHEMBL31596316 0.92 KMO (0.51) CAMKK2KMOCAMKK1ACMSD
SCHEMBL16584889 0.88 CAMKK2 (0.47) CAMKK2CAMKK1ACMSDKDM4E
SCHEMBL16584945 0.85 CAMKK2 (0.50) CAMKK2CAMKK1ACMSDKDM4E
SCHEMBL16584665 0.83 CAMKK2 (0.49) CAMKK2KMOCAMKK1ACMSDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418312-A Polymer properties THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1995-05-23 US claimed
US-5334752-A Difunctionalized to be incorporated into polymers for compressive strength THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF UNIVERSITY OF MICHIGAN (US) 1994-08-02 US claimed
WO-1994001388-A1 CYCLOBUTABENZENE MONOMERS AND METHODS OF MAKING AND USING SAME UNIVERSITY OF MICHIGAN (US) 1994-01-20 WO claimed
US-12630567-B2 High yield synthesis of metal-organic frameworks ExxonMobil Technology and Engineering Company (US) 2026-05-19 US disclosed
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
US-20240336636-A1 METAL-ORGANIC FRAMEWORK THE UNIVERSITY OF LIVERPOOL (GB) 2024-10-10 US disclosed
US-12107210-B2 Lithium-sulfur and sodium-sulfur battery cathodes THE JOHNS HOPKINS UNIVERSITY (US) 2024-10-01 US disclosed
US-20240294384-A1 MATERIAL, METHOD FOR PRODUCING MATERIAL AND FUNCTIONAL MATERIAL SEKISUI CHEMICAL CO., LTD. (JP) 2024-09-05 US disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP disclosed
US-12031014-B2 Composition, production method for molded object, and molded object SEKISUI CHEMICAL CO., LTD. (JP) 2024-07-09 US disclosed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 US disclosed
US-20070068389-A1 Metal-organic frameworks with exceptionally high capacity for storage of carbon dioxide at room-temperature THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2007-03-29 US disclosed
US-5770763-A POLYARYLCYCLOBUTENES DERIVED FROM 3,6 FUNCTIONALIZED MONO AND DICYCLOBUTABENZENE THE BOARD OF REGENTS OF THE UNIV. OF MICHIGAN (US) 1998-06-23 US disclosed
US-5552508-A Difunctional bitricyclodecatriene monomers UNIVERSITY OF MICHIGAN, THE BOARD OF REGENTS (US) 1996-09-03 US disclosed
US-5418312-A Polymer properties THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1995-05-23 US disclosed
US-5418312-A Polymer properties THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1995-05-23 US disclosed
US-5334752-A Difunctionalized to be incorporated into polymers for compressive strength THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF UNIVERSITY OF MICHIGAN (US) 1994-08-02 US disclosed
US-5334752-A Difunctionalized to be incorporated into polymers for compressive strength THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF UNIVERSITY OF MICHIGAN (US) 1994-08-02 US disclosed
WO-1994001388-A1 CYCLOBUTABENZENE MONOMERS AND METHODS OF MAKING AND USING SAME UNIVERSITY OF MICHIGAN (US) 1994-01-20 WO disclosed
WO-1994001388-A1 CYCLOBUTABENZENE MONOMERS AND METHODS OF MAKING AND USING SAME UNIVERSITY OF MICHIGAN (US) 1994-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630567-B2 High yield synthesis of metal-organic frameworks ODC1, POF1B, DDC CAMKK2 2374/4885KMO 2332/4885CAMKK1 2517/4885
US-12031014-B2 Composition, production method for molded object, and molded object ZKSCAN2, SLC39A3, CTCF CAMKK2 2701/4885KMO 195/4885CAMKK1 2776/4885
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 CAMKK2 4679/4885KMO 4412/4885CAMKK1 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.