SCHEMBL28170978

SCHEMBL28170978

O=C(O)c1ccc(C(=O)O)c(C2CCCC2)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CAMKK2 Q96RR4 16/20 0.52
KMO O15229 1/20 0.51
CAMKK1 Q8N5S9 12/20 0.48
ACMSD Q8TDX5 2/20 0.47
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448284 0.98 KMO (0.54) CAMKK2KMOCAMKK1ACMSD
SCHEMBL30952631 0.98 KMO (0.54) CAMKK2KMOCAMKK1ACMSD
SCHEMBL2445552 0.96 CAMKK2 (0.49) CAMKK2KMOCAMKK1ACMSDKDM4E
SCHEMBL29470084 0.96 CAMKK2 (0.49) CAMKK2KMOCAMKK1ACMSDKDM4E
Methyl Alcohol SCHEMBL31596316 0.95 KMO (0.51) CAMKK2KMOCAMKK1ACMSD
SCHEMBL29154739 0.93 KDM4E (0.46) CAMKK2KMOCAMKK1KDM4E
SCHEMBL28170365 0.93 KDM4E (0.46) CAMKK2KMOCAMKK1KDM4E
SCHEMBL16584945 0.88 CAMKK2 (0.50) CAMKK2CAMKK1ACMSDKDM4E
SCHEMBL16584665 0.87 CAMKK2 (0.49) CAMKK2KMOCAMKK1ACMSDKDM4E
SCHEMBL16584889 0.85 CAMKK2 (0.47) CAMKK2CAMKK1ACMSDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105764883-B Thermoplastic polymer composition 美利肯公司 2019-06-04 CN disclosed
CN-105764971-B Thermoplastic polymer composition 美利肯公司 2018-04-06 CN disclosed
CN-105745264-B Thermoplastic polymer composition 美利肯公司 2018-03-13 CN disclosed
CN-105745189-B Thermoplastic polymer composition 美利肯公司 2017-11-21 CN disclosed