Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438773 | 0.84 | CHRNB2 (0.50) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL19750413 | 0.83 | ACHE (0.53) | ACHECHRNB2CHRNA4CA12CA1 | |
| SCHEMBL13404615 | 0.79 | TSHR (0.44) | ACHECHRNB2NFKB1MAPK1CHRNA4 | |
| SCHEMBL15081505 | 0.77 | MAPK1 (0.34) | MAPK1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL1476342 | 0.76 | ALDH1A1 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL1142431 | 0.75 | MEN1 (0.30) | — | |
| SCHEMBL615943 | 0.74 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL17206238 | 0.74 | LMNA (0.46) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL1142076 | 0.73 | TSHR (0.43) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL19750483 | 0.73 | EPHX1 (0.59) | SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112136-B1 | BIS(2-ALKOXYETHYL) AZODICARBOXYLATE ESTER COMPOUND AND INTERMEDIATE FOR PRODUCTION OF THE SAME | TOYO BOSEKI (JP) | 2012-05-23 | — | — | EP | disclosed |
| US-7820802-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYOBO MC CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |