Thiabendazole

Thiabendazole

SCHEMBL28170923

O=C(O)Nc1ccccc1.c1ccc2[nH]c(-c3cscn3)nc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 8/20 0.71
METAP2 P50579 5/20 0.71
KDM4E B2RXH2 1/20 0.71
NPC1 O15118 1/20 0.71
TP53 P04637 1/20 0.71
CYP1A2 P05177 1/20 0.71
CYP3A4 P08684 1/20 0.71
ADORA3 P0DMS8 1/20 0.71
CYP2D6 P10635 1/20 0.71
TSHR P16473 1/20 0.71
CYP2C19 P33261 1/20 0.71
RAB9A P51151 1/20 0.71
FKBP1A P62942 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
HIF1A Q16665 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
HDAC6 Q9UBN7 1/20 0.71
HPSE Q9Y251 2/20 0.50
MMP2 P08253 3/20 0.49
MMP9 P14780 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiabendazole SCHEMBL28860081 0.86 METAP1 (0.81) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL19842 0.84 METAP1 (1.00) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL625588 0.84 METAP1 (1.00) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL29370729 0.84 METAP1 (1.00) METAP1METAP2KDM4ENPC1TP53
SCHEMBL11208569 0.84 METAP1 (0.55) METAP1METAP2KDM4ENPC1TP53
SCHEMBL11208586 0.84 METAP1 (0.63) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL724613 0.84 METAP1 (0.77) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL11570001 0.84 METAP1 (0.77) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL10618141 0.84 METAP1 (0.68) METAP1METAP2KDM4ENPC1TP53
Thiabendazole SCHEMBL2314460 0.83 METAP1 (0.97) METAP1METAP2KDM4ENPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107136059-A Agriculture chemistry composite particles and its manufacture method 住友化学株式会社 2017-09-08 CN disclosed