Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815533 | 0.79 | MAPT (0.44) | ALOX5ALDH1A1RAB9ANPC1LMNA | |
| Bromide SCHEMBL2818346 | 0.78 | MAPT (0.43) | ALOX5ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL2815003 | 0.72 | HRH3 (0.39) | ALOX5ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL1988355 | 0.71 | RAB9A (0.68) | ALDH1A1RAB9ANPC1LMNAGAA | |
| SCHEMBL4311317 | 0.71 | MAPT (0.57) | ALDH1A1RAB9ANPC1LMNAGAA | |
| SCHEMBL1691790 | 0.71 | ALOX5 (0.56) | ALOX5ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL15110953 | 0.69 | KDM4C (0.34) | ALDH1A1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13177316 | 0.69 | TP53 (0.62) | ALOX5ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL1691399 | 0.68 | TSPO (0.57) | ALOX5ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL7998877 | 0.68 | MCHR1 (0.36) | ALDH1A1GAAPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2213672-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249418-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APP, APBA1, C1QBP | ALOX5 3691/4885ALDH1A1 1923/4885RAB9A 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.