Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544790 | 0.83 | LOXL2 (0.44) | CYP11B2CYP11B1CYP19A1FNTAFNTB | |
| SCHEMBL28174136 | 0.79 | SOS1 (0.47) | CYP11B2CYP11B1CYP19A1MAPTTHRB | |
| SCHEMBL14203996 | 0.76 | CYP11B2 (0.44) | RAB9ACYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL28174160 | 0.75 | HTT (0.43) | CYP11B2CYP11B1CYP19A1MAPTTHRB | |
| SCHEMBL28175140 | 0.74 | OPRK1 (0.42) | RAB9ACYP11B2CYP11B1FNTAFNTB | |
| SCHEMBL5275734 | 0.72 | — | — | |
| SCHEMBL14477376 | 0.71 | FNTA (0.41) | RAB9ACYP11B2CYP11B1CYP19A1FNTA | |
| SCHEMBL14476266 | 0.71 | HPGD (0.32) | CYP11B2CYP11B1CYP19A1FNTAFNTB | |
| SCHEMBL12795863 | 0.71 | CYP11B2 (0.42) | RAB9ACYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL14476254 | 0.70 | TP53 (0.43) | RAB9ACYP11B2CYP11B1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074807-A | Compositions and methods for inhibiting histone demethylase | 吉利德科学公司 | 2017-08-18 | — | — | CN | disclosed |