Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12596283 | 0.84 | KCNH2 (0.61) | KCNH2CYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL14476635 | 0.82 | KCNH2 (0.46) | KCNH2CYP11B2CYP11B1CYP19A1P2RX7 | |
| SCHEMBL20413799 | 0.79 | QPCTL (0.52) | KCNH2CYP11B2CYP11B1MAPTP2RX7 | |
| SCHEMBL28174173 | 0.79 | RAB9A (0.46) | SOS1CYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL14203996 | 0.79 | CYP11B2 (0.44) | SOS1CYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL28174160 | 0.78 | HTT (0.43) | SOS1CYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL21083579 | 0.78 | CYP11B1 (0.41) | CYP11B2CYP11B1CYP19A1P2RX7 | |
| SCHEMBL14476844 | 0.78 | P2RX7 (0.54) | KCNH2P2RX7LMNA | |
| SCHEMBL17544790 | 0.76 | LOXL2 (0.44) | SOS1CYP11B2CYP11B1CYP19A1SLC2A1 | |
| SCHEMBL415170 | 0.75 | P2RX7 (0.45) | CYP11B2CYP11B1P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074807-A | Compositions and methods for inhibiting histone demethylase | 吉利德科学公司 | 2017-08-18 | — | — | CN | disclosed |