Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518384 | 0.87 | TSHR (0.47) | ALDH1A1TSHRACHEHPGDRAB9A | |
| SCHEMBL6626633 | 0.84 | TSHR (0.45) | ALDH1A1TSHRACHEHPGDRAB9A | |
| SCHEMBL28174458 | 0.83 | ALDH1A1 (0.38) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL28174457 | 0.79 | CRHBP (0.37) | ALDH1A1MAPK1MAOB | |
| SCHEMBL3170616 | 0.76 | TSHR (0.41) | ALDH1A1TSHRACHEHPGDRAB9A | |
| SCHEMBL10528475 | 0.75 | ACHE (0.50) | ALDH1A1TSHRACHEHPGDRAB9A | |
| SCHEMBL23600021 | 0.74 | CA1 (0.32) | ALDH1A1HPGDMAPK1CA1CA2 | |
| SCHEMBL471978 | 0.74 | NPSR1 (0.49) | ALDH1A1TSHRACHEHPGDMAPT | |
| SCHEMBL2552588 | 0.74 | NPSR1 (0.44) | ALDH1A1TSHRACHEHPGDMAPT | |
| SCHEMBL14339299 | 0.74 | LMNA (0.42) | ALDH1A1TSHRACHEHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226827-A | A kind of preparation method of chiral phosphorus fluorenes oxide | 杭州师范大学 | 2017-10-03 | — | — | CN | disclosed |