Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225239 | 0.86 | GAA (0.63) | HPGDNFKB1ALOX5CA2KDM4E | |
| SCHEMBL27854362 | 0.83 | FFAR4 (0.46) | HPGDNFKB1NPC1STAT1RAB9A | |
| SCHEMBL1815685 | 0.80 | CYP1A2 (0.50) | HPGDNFKB1NPC1STAT1RAB9A | |
| SCHEMBL9207785 | 0.79 | GAA (0.56) | HPGDNFKB1NPC1RAB9ANFKB2 | |
| SCHEMBL2807447 | 0.78 | CSNK2A1 (0.65) | HPGDALOX5ALDH1A1BACE1HSD17B10 | |
| SCHEMBL2734611 | 0.77 | KDM4E (0.67) | HPGDNFKB1CA2KDM4EALDH1A1 | |
| SCHEMBL14832184 | 0.77 | ALOX5 (0.59) | HPGDALOX5ALDH1A1BACE1HSD17B10 | |
| SCHEMBL1395755 | 0.77 | LMNA (0.69) | HPGDNFKB1NPC1STAT1RAB9A | |
| SCHEMBL254913 | 0.77 | RORC (0.54) | HPGDNFKB1NPC1STAT1RAB9A | |
| Hydrochloric Acid SCHEMBL21382514 | 0.76 | LMNA (0.67) | HPGDNFKB1NPC1STAT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024259-B | It is used as the triazolopyridazine derivates of 6 substitutions of Rev Erb activators | 基恩菲特公司 | 2017-09-26 | — | — | CN | disclosed |