Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737932 | 0.80 | PTGDR2 (0.41) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL20562760 | 0.80 | PTGDR2 (0.41) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL20564011 | 0.79 | PTGDR2 (0.41) | PDE4AL3MBTL1PTGER1PTGDR2MEN1 | |
| SCHEMBL28176696 | 0.79 | L3MBTL1 (0.32) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL28080077 | 0.78 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL20563124 | 0.77 | L3MBTL1 (0.38) | L3MBTL1PTGER1MEN1MAPTKMT2A | |
| SCHEMBL29737960 | 0.77 | L3MBTL1 (0.38) | L3MBTL1PTGER1MEN1MAPTKMT2A | |
| SCHEMBL30994653 | 0.76 | SLC6A4 (0.33) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL21940078 | 0.76 | CCR5 (0.39) | L3MBTL1PTGER1 | |
| SCHEMBL20562595 | 0.76 | L3MBTL1 (0.37) | L3MBTL1PTGER1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517574-B | The combination product of hepatitis C virus inhibitors | 百时美施贵宝公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-104302290-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-10-24 | — | — | CN | disclosed |