Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBS | P35520 | 1/20 | 0.63 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15194206 | 0.89 | CA12 (0.59) | CBSCYP3A4CA12CA4CA7 | |
| SCHEMBL572227 | 0.87 | CBS (0.59) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL572246 | 0.83 | CA12 (0.56) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL13963385 | 0.77 | CBS (1.00) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL13973879 | 0.77 | CBS (1.00) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL24464005 | 0.77 | CBS (0.88) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL29753914 | 0.77 | CBS (0.88) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL24464006 | 0.77 | CBS (0.88) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL161773 | 0.77 | CBS (0.88) | CBSNQO2CYP3A4CA12CA4 | |
| SCHEMBL16131011 | 0.77 | CBS (1.00) | CBSNQO2CYP3A4CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633166-B2 | Methicillin-resistant Staphylococcus aureus active metabolites | HAMANN, MARK T. | 2014-01-21 | — | — | US | disclosed |
| US-8633166-B2 | Methicillin-resistant Staphylococcus aureus active metabolites | HAMANN, MARK T. | 2014-01-21 | — | — | US | disclosed |
| US-20100273726-A1 | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF | TRITON BIOPHARMA (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273726-A1 | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF | TRITON BIOPHARMA (US) | 2010-10-28 | — | — | US | disclosed |
| WO-2010107793-A1 | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES | THE UNIVERSITY OF MISSISSIPPI (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100234311-A1 | Methicillin-Resistant Staphylococcus Aureus Active Metabolites | THE UNIVERSITY OF MISSISSIPPI (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234311-A1 | Methicillin-Resistant Staphylococcus Aureus Active Metabolites | THE UNIVERSITY OF MISSISSIPPI (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273726-A1 | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF | MRPS18A, CD14, MRPL38 | CBS 4674/4885NQO2 3138/4885CYP3A4 3662/4885 |
| US-20100234311-A1 | Methicillin-Resistant Staphylococcus Aureus Active Metabolites | HM13, FOS, MRPS23 | CBS 4757/4885NQO2 1995/4885CYP3A4 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.