Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386746 | 1.00 | ALOX5 (0.58) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL28589887 | 0.94 | ALOX5 (0.52) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| Propionic Acid SCHEMBL29128109 | 0.88 | ALOX5 (0.47) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL27896459 | 0.81 | ALOX5 (0.40) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL31054347 | 0.81 | HSD11B1 (0.38) | ALOX5HSD11B1MALT1TRPA1 | |
| SCHEMBL5768412 | 0.73 | ALOX5 (1.00) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL31021926 | 0.73 | ALOX5 (1.00) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL19062530 | 0.72 | ALOX5 (0.64) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL8299219 | 0.72 | LMNA (0.59) | HSD11B1MALT1TRPA1 | |
| SCHEMBL28179378 | 0.71 | HSD11B1 (0.39) | HSD11B1MALT1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024509-B | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-113024509-A | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-113024509-B | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-113024509-B | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-113024509-A | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-113024509-A | Preparation method of key intermediate of 3-bromo-1- (3-chloro-2-pyridyl) -1H-imidazole-5-formic acid | 杭州新桂实业有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-107163024-A | A kind of synthetic method of the Ethyl formate of 2 (pyridine radicals of 3 chlorine 2) 5 pyrazolidone 3 | 安徽星宇化工有限公司 | 2017-09-15 | — | — | CN | disclosed |