Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178496 | 0.88 | ALOX5 (0.58) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL29386746 | 0.88 | ALOX5 (0.58) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL28589887 | 0.83 | ALOX5 (0.52) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL27896459 | 0.78 | ALOX5 (0.40) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL31054347 | 0.71 | HSD11B1 (0.38) | ALOX5MALT1TRPA1 | |
| SCHEMBL29276397 | 0.68 | HSD11B1 (0.38) | MALT1TRPA1 | |
| SCHEMBL29139379 | 0.67 | CYP2C19 (0.39) | MALT1ALDH1A1MAPTTRPA1 | |
| SCHEMBL23005388 | 0.66 | MALT1 (0.42) | MALT1TRPA1 | |
| SCHEMBL951112 | 0.65 | CYP2C19 (0.44) | ALOX15ALOX12MALT1ALDH1A1MAPT | |
| SCHEMBL29386992 | 0.65 | HSD11B1 (0.40) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057687-B | Preparation method of pyridyl pyrazolone carboxylic ester compound | 沈阳中化农药化工研发有限公司 | 2023-11-14 | — | — | CN | disclosed |