SCHEMBL28178564

SCHEMBL28178564

COOc1ccccc1C(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.61
TSHR P16473 2/20 0.57
LMNA P02545 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CFTR P13569 1/20 0.55
SLC6A4 P31645 2/20 0.54
KDM4E B2RXH2 1/20 0.53
POLB P06746 1/20 0.53
ATM Q13315 1/20 0.53
KMT2A Q03164 4/20 0.53
HTT P42858 1/20 0.53
MAPT P10636 3/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 1/20 0.51
MEN1 O00255 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA5A P35218 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2441955 0.83 SLC6A3 (0.65) SLC6A3TSHRLMNAL3MBTL1HSD17B10
Methyl 2-Methoxybenzoate SCHEMBL29702077 0.83 TSHR (0.69) SLC6A3TSHRLMNAL3MBTL1HSD17B10
Methyl 2-Methoxybenzoate SCHEMBL196037 0.83 TSHR (0.69) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL29022476 0.83 SLC6A3 (0.47) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL9846404 0.83 SLC6A3 (0.56) SLC6A3TSHRLMNAL3MBTL1HSD17B10
Methyl 2-Methoxybenzoate SCHEMBL30744939 0.82 MAPT (0.67) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL28432969 0.82 KMT2A (0.63) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL28176283 0.82 SLC6A3 (0.62) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL4199247 0.82 SLC6A3 (0.62) SLC6A3TSHRLMNAL3MBTL1HSD17B10
SCHEMBL5459 0.82 KDM4E (0.61) TSHRLMNAHSD17B10ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207994-A Photolabile acetal and ketal compounds for controlled release of active volatile carbonyl compounds 弗门尼舍有限公司 2017-09-26 CN disclosed