Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178564 | 0.83 | SLC6A3 (0.61) | SLC6A3LMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL19137414 | 0.83 | LMNA (0.53) | LMNATSHRL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL1162463 | 0.81 | KDM4E (0.69) | SLC6A3LMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL30941613 | 0.81 | KDM4E (0.69) | SLC6A3LMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL11696928 | 0.81 | KDM4E (0.67) | LMNATSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL6116127 | 0.81 | TSHR (0.62) | LMNATSHRL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL11010377 | 0.80 | KDM4E (0.46) | SLC6A3LMNATSHRHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31169322 | 0.80 | KDM4E (0.67) | SLC6A3LMNATSHRL3MBTL1HSD17B10 | |
| Ethane SCHEMBL2712758 | 0.80 | KDM4E (0.65) | LMNATSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL828640 | 0.80 | IRAK4 (0.56) | SLC6A3LMNATSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |