Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178688 | 0.78 | PDE4A (0.50) | KMT2AP2RX7MAPTLMNAALDH1A1 | |
| SCHEMBL28179450 | 0.78 | TUBB4A (0.47) | TP53KMT2AP2RX7MAPTLMNA | |
| SCHEMBL14324139 | 0.78 | LMNA (0.57) | TP53KMT2AP2RX7TDP1MAPT | |
| SCHEMBL14324044 | 0.78 | HDAC8 (0.58) | TP53KMT2AGFERCXCR2P2RX7 | |
| SCHEMBL7599289 | 0.76 | ALDH1A1 (0.51) | TP53KMT2AP2RX7TDP1MAPT | |
| SCHEMBL28179465 | 0.75 | CYP11B1 (0.56) | TP53KMT2ACXCR2MAPTLMNA | |
| SCHEMBL17975189 | 0.73 | HDAC6 (0.41) | P2RX7TDP1ALDH1A1KDM4EHDAC8 | |
| SCHEMBL29079807 | 0.73 | APP (0.46) | TP53KMT2AALDH1A1 | |
| SCHEMBL27502740 | 0.73 | ALDH1A1 (0.42) | KMT2ATDP1MAPTLMNAALDH1A1 | |
| SCHEMBL28110914 | 0.72 | CYP11B1 (0.55) | MAPTLMNAALDH1A1KDM4EHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |