Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992859 | 0.89 | REV1 (0.53) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28179450 | 0.86 | TUBB4A (0.47) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28179447 | 0.81 | REV1 (0.50) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28179465 | 0.81 | CYP11B1 (0.56) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28178546 | 0.80 | SIGMAR1 (0.55) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28179434 | 0.78 | TP53 (0.49) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL28179433 | 0.76 | REV1 (0.50) | KMT2AALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL28110914 | 0.76 | CYP11B1 (0.55) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL5444593 | 0.75 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3613434 | 0.75 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |