Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL3397874 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Salicylic Acid SCHEMBL22022712 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Salicylic Acid SCHEMBL2898273 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Salicylic Acid SCHEMBL9813624 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Salicylic Acid SCHEMBL980591 | 0.72 | ALDH1A1 (0.95) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL5954312 | 0.72 | ALDH1A1 (0.95) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL29386727 | 0.72 | ALDH1A1 (0.95) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL980590 | 0.72 | ALDH1A1 (0.95) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL28160119 | 0.70 | ALDH1A1 (0.62) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| Salicylic Acid SCHEMBL8029424 | 0.70 | ALDH1A1 (0.90) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107255685-A | The high performance liquid chromatography of ultraviolet absorber in a kind of detection cosmetics | 厦门鉴科检测技术有限公司 | 2017-10-17 | — | — | CN | disclosed |