Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL2898273 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Salicylic Acid SCHEMBL22022712 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Salicylic Acid SCHEMBL28181702 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Salicylic Acid SCHEMBL9813624 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Salicylic Acid SCHEMBL28653381 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Acetic Acid SCHEMBL11223879 | 0.76 | APLNR (0.46) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| Homosalate SCHEMBL2808104 | 0.75 | ALDH1A1 (0.97) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL113337 | 0.74 | APLNR (0.39) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL1358694 | 0.74 | APLNR (0.39) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL1411809 | 0.74 | APLNR (0.39) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9442219-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2016-09-13 | — | — | US | claimed |
| US-20140329008-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | CERTAINTEED LLC | 2014-11-06 | — | — | US | claimed |
| US-8790778-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2014-07-29 | — | — | US | claimed |
| US-20130161578-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | SHIAO MING LIANG (US) | 2013-06-27 | — | — | US | claimed |
| US-8394498-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2013-03-12 | — | — | US | claimed |
| US-20100151199-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | CERTAINTEED CORPORATION | 2010-06-17 | — | — | US | claimed |
| US-9442219-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| US-20140329008-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | CERTAINTEED LLC | 2014-11-06 | — | — | US | disclosed |
| CN-104045561-A | Synthetic method for 3,3,5-trimethylcyclohexanol salicylate | LIAONING DEFENG PHARMACEUTICAL & CHEMICAL CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-104045561-A | Synthetic method for 3,3,5-trimethylcyclohexanol salicylate | LIAONING DEFENG PHARMACEUTICAL & CHEMICAL CO LTD | 2014-09-17 | — | — | CN | disclosed |
| US-8790778-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2014-07-29 | — | — | US | disclosed |
| US-20130161578-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | SHIAO MING LIANG (US) | 2013-06-27 | — | — | US | disclosed |
| US-8394498-B2 | Roofing granules with high solar reflectance, roofing materials with high solar reflectance, and the process of making the same | CERTAINTEED CORPORATION (US) | 2013-03-12 | — | — | US | disclosed |
| US-20100151199-A1 | ROOFING GRANULES WITH HIGH SOLAR REFLECTANCE, ROOFING MATERIALS WITH HIGH SOLAR REFLECTANCE, AND THE PROCESS OF MAKING THE SAME | CERTAINTEED CORPORATION | 2010-06-17 | — | — | US | disclosed |
| CN-1139587-C | Cosmetic preparation containing light stable UV-A light filter agent | 巴斯福股份公司 | 2004-02-25 | — | — | CN | disclosed |
| CN-1377883-A | Cosmetic preparation containing light stable UV-A light filter agent | BASF AG (DE) | 2002-11-06 | — | — | CN | disclosed |
| CN-1082362-C | Cosmetic preparation containing photostable UV-A filter | BASF AG (DE) | 2002-04-10 | — | — | CN | disclosed |
| CN-1176097-A | Cosmetic preparation containing photostable UV-A filter | BASF AG (DE) | 1998-03-18 | — | — | CN | disclosed |