Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 9/20 | 0.54 |
| ▸ | TACR3 | P29371 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581556 | 0.81 | CYP2D6 (1.00) | CYP2D6CYP2C19GAACYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3326324 | 0.80 | CYP2D6 (0.97) | CYP2D6CYP2C19GAACYP2C9ALDH1A1 | |
| SCHEMBL18075786 | 0.78 | ALDH1A1 (0.75) | CYP2D6CYP2C19GAACYP2C9ALDH1A1 | |
| SCHEMBL2372698 | 0.69 | DHODH (0.56) | CYP2D6CYP2C19CYP2C9ALDH1A1DHODH | |
| SCHEMBL28170815 | 0.69 | DHODH (0.73) | GAADHODHPDE10ATSHR | |
| SCHEMBL17594326 | 0.69 | PTGFR (0.55) | DHODHTACR3PTGFR | |
| SCHEMBL22734576 | 0.67 | P2RX3 (0.45) | GAAALDH1A1DHODHPDE10APRNP | |
| SCHEMBL4228780 | 0.67 | DHODH (0.70) | GAADHODHPDE10ATSHR | |
| SCHEMBL1581075 | 0.67 | CYP2D6 (0.72) | CYP2D6CYP2C19GAACYP2C9ALDH1A1 | |
| SCHEMBL20138876 | 0.67 | PDE10A (0.40) | GAAALDH1A1DHODHPDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428691-A | Bicyclic formamides of 2 aryl quinoline 4 of substituted N and application thereof | 拜耳制药股份公司 | 2017-12-01 | — | — | CN | disclosed |