Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185545 | 0.82 | NOTUM (0.42) | NOTUMNPC1RAB9ALMNAGPBAR1 | |
| SCHEMBL28185541 | 0.78 | RAB9A (0.45) | MEN1KMT2ANOTUMMAPK13MAPK12 | |
| SCHEMBL3659068 | 0.75 | KIF11 (0.47) | MEN1KMT2AKIF11GSRMKNK1 | |
| SCHEMBL28186260 | 0.72 | MAPT (0.45) | MEN1KMT2AKIF11GSRLMNA | |
| SCHEMBL28186241 | 0.72 | NOTUM (0.39) | NOTUMGPBAR1 | |
| SCHEMBL5774283 | 0.71 | HIF1A (0.41) | MEN1KMT2AKIF11GSRMKNK1 | |
| SCHEMBL5773073 | 0.71 | GSR (0.41) | MEN1KMT2AKIF11GSRMKNK1 | |
| SCHEMBL5773336 | 0.68 | FFAR4 (0.48) | — | |
| SCHEMBL27809403 | 0.67 | CYP2C8 (0.46) | KIF11NPC1RAB9ALMNAIKBKB | |
| SCHEMBL5773409 | 0.66 | MAPT (0.49) | MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382892-A | A kind of preparation technology of the nitro isoxazole compound of 3 aryl 4 | 贵州大学 | 2017-11-24 | — | — | CN | disclosed |