Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LPO | P22079 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267508 | 0.80 | LMNA (0.48) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL17912992 | 0.76 | PKM (0.79) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL17912981 | 0.75 | MEN1 (0.56) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL28868418 | 0.75 | LMNA (0.46) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL19643992 | 0.75 | LMNA (0.46) | LMNAHTTALOX15TSHRPKM | |
| Hydrochloric Acid SCHEMBL27805112 | 0.74 | SIGMAR1 (0.58) | LMNAPKMLPOSIGMAR1CMA1 | |
| SCHEMBL28266102 | 0.74 | LMNA (0.50) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL28266159 | 0.73 | LMNA (0.44) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL19759541 | 0.72 | CMA1 (0.51) | LMNAHTTALOX15TSHRPKM | |
| SCHEMBL28186296 | 0.72 | MAPT (0.56) | LMNAHTTALOX15TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406426-A | Cyclic ureas as ROCK inhibitors | 百时美施贵宝公司 | 2017-11-28 | — | — | CN | disclosed |