SCHEMBL28187128

SCHEMBL28187128

O=[N+]([O-])c1cc(-c2ccc(O)cc2)ccc1NCCO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
MAPT P10636 6/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
GALR3 O60755 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PKM P14618 1/20 0.52
ABCB1 P08183 2/20 0.48
ABCC1 P33527 2/20 0.48
RAB9A P51151 2/20 0.48
KMT2A Q03164 1/20 0.47
PRSS1 P07477 3/20 0.46
HCAR3 P49019 1/20 0.46
AURKA O14965 1/20 0.45
PLK1 P53350 1/20 0.45
DYRK1A Q13627 1/20 0.45
MARK2 Q7KZI7 1/20 0.45
AURKB Q96GD4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410422 0.88 ALDH1A1 (0.63) ALDH1A1TSHRTDP1MAPTLMNA
SCHEMBL24055 0.88 ALDH1A1 (0.63) ALDH1A1TSHRTDP1MAPTLMNA
Bromide SCHEMBL28440810 0.87 ALDH1A1 (0.62) ALDH1A1TSHRTDP1MAPTLMNA
Methoxymethane SCHEMBL7085872 0.83 ALDH1A1 (0.58) ALDH1A1TSHRTDP1MAPTLMNA
SCHEMBL6001854 0.82 TDP1 (0.56) ALDH1A1TSHRTDP1MAPTLMNA
SCHEMBL111519 0.79 PRSS1 (0.55) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL127370 0.79 ALDH1A1 (0.68) ALDH1A1TSHRTDP1MAPTLMNA
SCHEMBL29392416 0.79 ALDH1A1 (0.68) ALDH1A1TSHRTDP1MAPTLMNA
SCHEMBL563763 0.79 PKM (0.67) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL8053888 0.79 ALDH1A1 (0.63) ALDH1A1TSHRTDP1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428709-A Cation direct dye 巴斯夫欧洲公司 2017-12-01 CN disclosed