SCHEMBL29410422

SCHEMBL29410422

O=[N+]([O-])c1cc(O)ccc1NCCO

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
TSHR P16473 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
PKM P14618 1/20 0.56
RAB9A P51151 2/20 0.56
MAPT P10636 5/20 0.55
KMT2A Q03164 1/20 0.51
PRSS1 P07477 4/20 0.50
HCAR3 P49019 3/20 0.50
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
GALR3 O60755 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KAT2B Q92831 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24055 1.00 ALDH1A1 (0.63) ALDH1A1TSHRTDP1PKMRAB9A
Bromide SCHEMBL28440810 0.98 ALDH1A1 (0.62) ALDH1A1TSHRTDP1PKMRAB9A
Methoxymethane SCHEMBL7085872 0.94 ALDH1A1 (0.58) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL6001854 0.93 TDP1 (0.56) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL111519 0.91 PRSS1 (0.55) ALDH1A1TSHRTDP1PKMMAPT
3-Nitro-Phenol SCHEMBL7120003 0.89 PKM (0.67) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL28187128 0.88 ALDH1A1 (0.58) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL23456361 0.88 PKM (0.53) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL1814295 0.88 ALDH1A1 (0.55) ALDH1A1TSHRTDP1PKMRAB9A
SCHEMBL9652783 0.87 RAB9A (0.56) ALDH1A1TSHRTDP1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
EP-4076353-A1 TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE Henkel AG & Co. KGaA (DE) 2022-10-26 EP claimed
EP-4743055-A1 OXIDATIVE HAIR TREATMENT COMPOSITIONS COMPRISING POLYETHERS Wella Germany GmbH (DE) 2026-05-20 EP disclosed
WO-2025216848-A1 HOME AND PERSONAL CARE FORMULATIONS COMPRISING 3-AMINO-2-BUTANOL AND USE THEREOF ADVANCION CORPORATION (US) 2025-10-16 WO disclosed
WO-2025087607-A1 INORGANIC-ORGANIC DIAMINE CROSSLINKER FOR IMPROVING THE CONDITION OF HAIR DURING USE OF OXIDATIVE HAIR TREATMENT AGENTS HENKEL AG & CO. KGAA (DE) 2025-05-01 WO disclosed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP disclosed
WO-2025016926-A1 OXIDATIVE HAIR TREATMENT COMPOSITIONS COMPRISING POLYETHERS Wella GmbH (DE) 2025-01-23 WO disclosed
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product HENKEL AG & CO. KGAA (DE) 2024-08-27 US disclosed
CN-118524826-A By mixing organic C in a specific molar ratio1-C6Method for producing hair treatment products from alkoxysilanes and alkalizers 汉高股份有限及两合公司 2024-08-20 CN disclosed
CN-118201588-A Alkaline solvent hair pre-wash for optimizing wash stability of grade 1 dyeing 汉高股份有限及两合公司 2024-06-14 CN disclosed
CN-117897134-A Method for dyeing keratin materials, in particular human hair 汉高股份有限及两合公司 2024-04-16 CN disclosed
EP-4065070-A1 METHOD FOR IMPROVING THE TACTILE SENSATION OF DYED KERATINOUS MATERIAL, ESPECIALLY HUMAN HAIR Henkel AG & Co. KGaA (DE) 2022-10-05 EP disclosed
EP-4065079-A1 METHOD FOR IMPROVING COLOUR RETENTION OF DYED KERATINOUS MATERIAL, ESPECIALLY HUMAN HAIR Henkel AG & Co. KGaA (DE) 2022-10-05 EP disclosed
WO-2022182596-A1 SUBSTITUTION OF AMMONIA IN HAIR ALTERING PRODUCTS ANGUS CHEMICAL COMPANY (US) 2022-09-01 WO disclosed
CN-114746076-A Performance of pigment-based colorants through the use of a pretreatment 汉高股份有限及两合公司 2022-07-12 CN disclosed
CN-114727925-A Method for improving the tactile sensation of pigmented keratin materials, in particular human hair 汉高股份有限及两合公司 2022-07-08 CN disclosed
CN-114727932-A Method for bleaching keratin materials which have been coloured with aminosilicones and pigments 汉高股份有限及两合公司 2022-07-08 CN disclosed
EP-4007562-A1 METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE USE OF AN ORGANIC C1-C6-ALKOXY-SILANE AND AN ALKALISING AGENT Henkel AG & Co. KGaA (DE) 2022-06-08 EP disclosed
EP-3999189-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A COLORED EFFECT PIGMENT AND A FILM-FORMING POLYMER II Henkel AG & Co. KGaA (DE) 2022-05-25 EP disclosed
EP-3958821-A1 REFLECTIVE COMPOSITION Theunseen Limited (GB) 2022-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product OGG1, ALPG, OAT ALDH1A1 1825/4885TSHR 3783/4885TDP1 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.