Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL27677791 | 0.90 | LMNA (0.42) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| 1,3-Propanediol SCHEMBL22733724 | 0.90 | TDP1 (0.47) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| Alcohol SCHEMBL6545350 | 0.90 | ALOX15 (0.42) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| SCHEMBL3094 | 0.89 | — | — | |
| SCHEMBL28902273 | 0.89 | DGAT1 (0.42) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| SCHEMBL28325001 | 0.89 | DGAT1 (0.42) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| SCHEMBL30234788 | 0.89 | DGAT1 (0.42) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| Methylamine SCHEMBL25305181 | 0.86 | DGAT1 (0.40) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL8549932 | 0.86 | DGAT1 (0.40) | TDP1ALOX15DGAT1LMNAHSD17B10 | |
| SCHEMBL28616368 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501378-A | A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-107501542-A | A kind of preparation method of Amino End Group polyethylene glycol t-butyl carbamate | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-107501378-B | A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof | 湖南华腾制药有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-107501378-B | A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof | 湖南华腾制药有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-107501378-A | A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107501542-A | A kind of preparation method of Amino End Group polyethylene glycol t-butyl carbamate | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107501542-A | A kind of preparation method of Amino End Group polyethylene glycol t-butyl carbamate | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107501542-A | A kind of preparation method of Amino End Group polyethylene glycol t-butyl carbamate | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107501378-A | A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof | 湖南华腾制药有限公司 | 2017-12-22 | — | — | CN | disclosed |