Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27464056 | 0.92 | ALOX15 (0.43) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| Propanol SCHEMBL27677791 | 0.90 | LMNA (0.42) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| Ethylamine SCHEMBL5574544 | 0.90 | ALOX15 (0.42) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| Ethylene Glycol SCHEMBL28188461 | 0.90 | TDP1 (0.41) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| Butane SCHEMBL27617980 | 0.90 | LMNA (0.45) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| SCHEMBL28902273 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| SCHEMBL28325001 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| SCHEMBL3094 | 0.89 | — | — | |
| SCHEMBL30234788 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10TDP1DGAT1 | |
| Bromoethane SCHEMBL8925398 | 0.87 | ALOX15 (0.40) | ALOX15LMNAHSD17B10TDP1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518044-A | Alkoxy isoxazole derivative and preparation method and application thereof | 华东师范大学 | 2020-08-11 | — | — | CN | disclosed |
| US-9012128-B2 | Photoresist and coated substrate comprising same | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-8722825-B2 | Surface active additive and photoresist composition comprising same | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| US-20140065540-A1 | PHOTORESIST AND COATED SUBSTRATE COMPRISING SAME | Rohm and Haas Electronic Materials (US) | 2014-03-06 | — | — | US | disclosed |
| US-20130137035-A1 | SURFACE ACTIVE ADDITIVE AND PHOTORESIST COMPOSITION COMPRISING SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-30 | — | — | US | disclosed |
| US-6696500-B2 | BIOACTIVE SUBSTANCE HAVING ACIDIC GROUP AND A BIODEGRADABLE POLYMER HAVING AN OPTIONALLY PROTECTED BASIC GROUP, SUCH AS A POLYLACTONE THAT HAS BEEN ESTERIFIED, AMIDATED, OR THIOESTERIFIED WITH A COMPOUND HAVING CYCLIC AMINO GROUPS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-0815853-B1 | Sustained-release preparation for bioactive substance having an acidic group | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-0874854-B1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS INC (US) | 2001-12-12 | — | — | EP | disclosed |
| US-20010038854-A1 | Sustained-release preparation | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2001-11-08 | — | — | US | disclosed |
| US-5859256-A | CHLORINATION; USEFUL AS ANTIBACTERIAL AGENTS AND IN TREATING DISEASES CAUSED BY ORGANISMS WHICH ARE RESISTANT TO BETA-LACTAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0815853-A2 | Sustained-release preparation for bioactive substance having an acidic group | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5599587-A | Phosphoric acid esters and their use in the preparation of biocompatible surfaces | BIOCOMPATIBLES LIMITED (GB) | 1997-02-04 | — | — | US | disclosed |
| EP-0426804-B1 | 2-(2-HYDROXY-3-PHENOXYPROPYLAMINO)-ETHOXYBENZENE DERIVATIVES | ICI PLC (GB) | 1994-01-19 | — | — | EP | disclosed |
| EP-0427480-B1 | 2-Hydroxy-3-phenoxypropylamino compounds | ICI PLC (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0565317-A1 | (2-(2-hydroxy-2 phenylethylamino)ethoxy) phenyl derivatives, processes and intermediates for their preparation, pharmaceutical compositions containing them and their use as Beta-3-adrenoceptor agonists | ZENECA LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |
| US-5187190-A | PHENOXYPROPANOLAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| EP-0427480-A1 | 2-Hydroxy-3-phenoxypropylamino compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-15 | — | — | EP | disclosed |
| EP-0426804-A1 | 2-(2-HYDROXY-3-PHENOXYPROPYLAMINO)-ETHOXYBENZENE DERIVATIVES. | ICI PLC (GB) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990013535-A1 | COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010038854-A1 | Sustained-release preparation | BMP2, PGF, AREG | ALOX15 1152/4885LMNA 1563/4885HSD17B10 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.