Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437046 | 0.82 | LMNA (0.46) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 | |
| Doxribtimine SCHEMBL2195275 | 0.76 | TK1 (0.52) | LMNASMN1; SMN2TK1TK2 | |
| 2,6-Diaminopurine SCHEMBL7801065 | 0.76 | PDPK1 (0.55) | ADRB1DNMT1PDPK1GDALMNA | |
| Deoxyguanosine SCHEMBL1666272 | 0.73 | POLB (0.56) | ADRB1DNMT1LMNASMN1; SMN2PNP | |
| 2,6-Diaminopurine SCHEMBL160630 | 0.72 | PDPK1 (0.52) | PDPK1GDAPNPMGMT | |
| SCHEMBL10674095 | 0.70 | DUT (0.42) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL4745548 | 0.69 | TK1 (0.43) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL292198 | 0.69 | LMNA (0.45) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL1583331 | 0.69 | TK1 (0.44) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 | |
| SCHEMBL15893327 | 0.69 | TK1 (0.44) | ADRB1DNMT1LMNASMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107753499-A | For treating the Compounds and methods for of virus infection | 春堤制药公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-103816174-B | For treating the Compounds and methods for of virus infection | 春堤制药公司 | 2017-12-05 | — | — | CN | disclosed |