Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 12/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 11/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 11/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | MGMT | P16455 | 6/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Diaminopurine SCHEMBL10774603 | 0.81 | PDPK1 (0.59) | PDPK1GDADNMT1CDK2DPP4 | |
| 2,6-Diaminopurine SCHEMBL2934952 | 0.81 | PDPK1 (0.59) | PDPK1GDADNMT1CDK2DPP4 | |
| 2,6-Diaminopurine SCHEMBL6241914 | 0.81 | PDPK1 (0.59) | PDPK1GDADNMT1CDK2DPP4 | |
| SCHEMBL7646510 | 0.81 | PDPK1 (0.41) | PDPK1GDAADRB1DNMT1CDK2 | |
| 2-Aminopurine SCHEMBL1919609 | 0.81 | ALDH1A1 (0.55) | PDPK1GDAADRB1DNMT1CDK2 | |
| 2,6-Diaminopurine SCHEMBL443468 | 0.81 | PDPK1 (0.55) | PDPK1GDACDK2DPP4CDK1 | |
| 2,6-Diaminopurine SCHEMBL2586310 | 0.80 | PDPK1 (0.56) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL7661702 | 0.78 | BRAF (0.43) | PDPK1GDACDK1 | |
| Doxribtimine SCHEMBL2195275 | 0.77 | TK1 (0.52) | LMNASMN1; SMN2 | |
| 2,6-Diaminopurine SCHEMBL28189513 | 0.76 | ADRB1 (0.41) | PDPK1GDAADRB1DNMT1MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074611-A | Method and polynucleotide for amplifying target polynucleotide | 牛津纳米孔科技公司 | 2020-12-11 | — | — | CN | disclosed |
| EP-1163251-A1 | N-ACYLPHOSPHORAMIDITES AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056749-A1 | N-ACYLPHOSPHORAMIDITES AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-09-28 | — | — | WO | disclosed |
| US-5166315-A | Polynucleotides for genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-11-24 | — | — | US | disclosed |