Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909362 | 0.83 | HPGD (0.56) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL1894982 | 0.83 | HPGD (0.56) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL28115672 | 0.81 | ALDH1A1 (0.51) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL27476164 | 0.81 | TAAR1 (0.48) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL27982253 | 0.81 | BCHE (0.49) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL7056829 | 0.81 | LTB4R (0.48) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL11442263 | 0.81 | TSHR (0.58) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL23027267 | 0.80 | LTB4R (0.54) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL13572924 | 0.80 | LTB4R (0.54) | LTB4RLTB4R2HPGDALDH1A1FFAR1 | |
| SCHEMBL30688108 | 0.80 | LTB4R (0.54) | LTB4RLTB4R2HPGDALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088096-A | Piperidine derivatives as inhibitors of ubiquitin-specific protease 7 | 阿尔麦克探索有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109790146-A | Medical compounds | 阿尔麦克探索有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-107406451-A | Pyrrolopyrimidines and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | 福马治疗股份有限公司 | 2017-11-28 | — | — | CN | disclosed |